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Abnova
ITGB8 Monoclonal Antibody (2B4)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00003696-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
2B4
抗原
ITGB8 (NP_002205, 392 a.a. approximately 503 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
Immunogen sequence: VENQVQGIYF NITAICPDGS RKPGMEGCRN VTSNDEVLFN VTVTMKKCDV TGGKNYAIIK PIGFNETAKI HIHRNCSCQC EDNRGPKGKC VDETFLDSKC FQCDENKCHF DE
靶标信息
ITGB8 (Integrin beta 8) is a member of the integrin beta chain family and is a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. In general, integrin complexes mediate cell-cell and cell-extracellular matrix interactions and this complex plays a role in human airway epithelial proliferation. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Integrin beta8; unnamed protein product
UniProt ID: (Human) P26012
Entrez Gene ID: (Human) 3696
vasculogenesis
cell adhesion
cell-matrix adhesion
cell surface receptor signaling pathway
integrin-mediated signaling pathway
anatomical structure morphogenesis
positive regulation of gene expression
negative regulation of gene expression
cell migration
cell differentiation
cell adhesion mediated by integrin
positive regulation of angiogenesis
cartilage development
placenta blood vessel development
cell-cell adhesion
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