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Invitrogen
ITIH4 Polyclonal Antibody
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产品信息
PA5-51641
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human ITIH4. Recombinant protein control fragment (Product #RP-100488).
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: QGVEVTGQYE REKAGFSWIE VTFKNPLVWV HASPEHVVVT RNRRSSAYKW KETLFSVMPG LKMTMDKTGL LLLSDPDKVT IGLLFWDGRG EGLRLLLRDT DRFSSHVGGT LGQFYQEVLW GSPAASDDGR RTLRVQGNDH
Highest antigen sequence identity to the following orthologs: Mouse - 59%, Rat - 60%.
靶标信息
The inter-alpha-trypsin inhibitor (ITI, I-alpha-I) family is a classic example of protein-glycosaminoglycoprotein (PGP) complexes. They occur constitutively in plasma at relatively high concentrations and results from alternating combinations of three kinds of heavy chains with a common light chain called the bikunin proteoglycan. Bikunin has two proteinase inhibotor domains and belongs to the Kunitz-type protease inhibitor family; it displays an inhibitory activity against trypsin, leukocyte elastase and plasmin. The heavy chains do not have any protease inhibitory properties but have the capacity to interact in vitro and in vivo with hyaluronic acid and this binding promotes the stability of the extra-cellular matrix. The ITI protein family is suspected of playing a key role in the extra-cellular matrix biology.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp686G21125; Gp120; IHRP; inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein); inter-alpha-inhibitor heavy chain 4; Inter-alpha-trypsin inhibitor family heavy chain-related protein; inter-alpha-trypsin inhibitor heavy chain family, member 4; Inter-alpha-trypsin inhibitor heavy chain H4; inter-alpha-trypsin inhibitor, heavy chain-like, 1; ITI heavy chain H4; Plasma kallikrein sensitive glycoprotein 120; plasma kallikrein-sensitive glycoprotein 120
基因别名: GP120; H4P; IHRP; ITI-HC4; ITIH4; ITIHL1; PK-120; PK120; PRO1851
UniProt ID: (Human) Q14624
Entrez Gene ID: (Human) 3700
