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Proteintech
ITPKA Polyclonal Antibody
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产品信息
14270-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ITPKA Fusion Protein Ag5588 (141-461 aa encoded by BC026331)
偶联物
形式
Liquid
浓度
0.18 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: LLSDSESRS RGNVQLEAGE DVGQKNHWQK IRTMVNLPVI SPFKKRYAWV QLAGHTGSFK AAGTSGLILK RCSEPERYCL ARLMADALRG CVPAFHGVVE RDGESYLQLQ DLLDGFDGPC VLDCKMGVRT YLEEELTKAR ERPKLRKDMY KKMLAVDPEA PTEEEHAQRA VTKPRYMQWR EGISSSTTLG FRIEGIKKAD GSCSTDFKTT RSREQVLRVF EEFVQGDEEV LRRYLNRLQQ IRDTLEVSEF FRRHEVIGSS LLFVHDHCHR AGVWLIDFGK TTPLPDGQIL DHRRPWEEGN REDGYLLGLD NLIGILASLA ER (141-461 aa encoded by BC026331)
靶标信息
Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: EC 2.7.1.127; inositol 1,4,5-triphosphate 3-kinase; Inositol 1,4,5-trisphosphate 3-kinase A; inositol 145-triphosphate 3-kinase; Inositol-trisphosphate 3-kinase A; insP 3-kinase A; IP3 3 kinase A; IP3 3-kinase A; IP3-kinase A; IP3K A
基因别名: IP3-3KA; IP3KA; ITPKA
UniProt ID: (Human) P23677, (Mouse) Q8R071, (Rat) P17105
Entrez Gene ID: (Human) 3706, (Mouse) 228550, (Rat) 81677
