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Abnova
ITPR1 Monoclonal Antibody (2B6)
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产品信息
H00003708-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
2B6
抗原
ITPR1 (NP_002213, 2470 a.a. approximately 2577 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.4 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Immunogen sequence: EHTCETLLMC IVTVLSHGLR SGGGVGDVLR KPSKEEPLFA ARVIYDLLFF FMVIIIVLNL IFGVIIDTFA DLRSEKQKKE EILKTTCFIC GLERDKFDNK TVTFEEHI
靶标信息
Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Inositol 1,4,5 trisphosphate receptor; Inositol 1,4,5-trisphosphate receptor type 1; Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1; IP3 receptor isoform 1; IP3R 1; SI-SIII-SIIA; Type 1 inositol 1,4,5-trisphosphate receptor; Type 1 InsP3 receptor
基因别名: INSP3R1; ITPR1
Entrez Gene ID: (Human) 3708
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