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Invitrogen
ITSN1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-68812
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
synthetic peptide directed towards the middle region of mouse ITSN1
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
50 µg
纯化类型
Affinity chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This target displays homology in the following species: Cow: 86%; Dog: 86%; Guinea Pig: 86%; Horse: 86%; Human: 86%; Mouse: 100%; Rabbit: 86%; Rat: 100%
靶标信息
The protein encoded by this gene is a cytoplasmic membrane-associated protein that indirectly coordinates endocytic membrane traffic with the actin assembly machinery. In addition, the encoded protein may regulate the formation of clathrin-coated vesicles and could be involved in synaptic vesicle recycling. This protein has been shown to interact with dynamin, CDC42, SNAP23, SNAP25, SPIN90, EPS15, EPN1, EPN2, and STN2. Multiple transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been characterized so far.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EH and SH3 domains protein 1; Eh domain, SH3 domain regulator of endocytosis 1; intersectin (SH3 domain protein 1A); intersectin short form 2 variant 2; Intersectin-1; intersectin-L; MGC134948; MGC134949
基因别名: AA517634; AA545208; AI316805; AI839402; AI848451; Ehsh1; Ese1; Itsn; Itsn1; Sh3p17
UniProt ID: (Mouse) Q9Z0R4
Entrez Gene ID: (Mouse) 16443
endocytosis
small GTPase mediated signal transduction
regulation of Rho protein signal transduction
intracellular signal transduction
positive regulation of phosphorylation
positive regulation of catalytic activity
negative regulation of neuron apoptotic process
positive regulation of protein kinase B signaling
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