Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
IVNS1ABP Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
产品信息
14741-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
IVNS1ABP Fusion Protein Ag6412 (301-633 aa encoded by BC067739)
偶联物
形式
Liquid
浓度
0.19 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: TYLCLAVLD GIFCVIFLHG RNSPQSSPTS TPKLSKSLSF EMQQDELIEK PMSPMQYARS GLGTAEMNGK LIAAGGYNRE ECLRTVECYN PHTDHWSFLA PMRTPRARFQ MAVLMGQLYV VGGSNGHSDD LSCGEMYDSN IDDWIPVPEL RTNRCNAGVC ALNGKLYIVG GSDPYGQKGL KNCDVFDPVT KLWTSCAPLN IRRHQSAVCE LGGYLYIIGG AESWNCLNTV ERYNPENNTW TLIAPMNVAR RGAGVAVLNG KLFVCGGFDG SHAISCVEMY DPTRNEWKMM GNMTSPRSNA GIATVGNTIY AVGGFDGNEF LNTVEVYNLE SNEW (301-633 aa encoded by B C067739)
靶标信息
IVNS1ABP is a protein coding gene involved in many cell functions, including pre-mRNA splicing, the aryl hydrocarbon receptor (AHR) pathway, F-actin organization and protein ubiquitination. Plays a role in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription. In addition, functions as a negative regulator of BCR(KLHL20) E3 ubiquitin ligase complex to prevent ubiquitin-mediated proteolysis of PML and DAPK1, two tumor suppressors. Inhibits pre-mRNA splicing (in vitro).; (Microbial infection) involved in the alternative splicing of influenza A virus M1 mRNA through interaction with HNRNPK, thereby facilitating the generation of viral M2 protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: aryl hydrocarbon receptor-associated 3; Aryl hydrocarbon receptor-associated protein 3; Influenza virus NS1A-binding protein; Influenza virus NS1A-binding protein homolog; kelch family protein Nd1; Kelch family protein Nd1-L; kelch-like family member 39; Kelch-like protein 39; NCX downstream gene 1; ND1-L2; Nd1-S; NS1-binding protein; NS1-binding protein homolog; NS1-BP
基因别名: 1190004M08Rik; 1700126I16Rik; AA960440; ARA3; FLARA3; HSPC068; IVNS1ABP; KIAA0850; KLHL39; mKIAA0850; ND1; Nd1-L; Nd1-S; Nd1L; Nd1S; NS-1; NS1; NS1-BP; NS1BP
UniProt ID: (Human) Q9Y6Y0, (Mouse) Q920Q8
Entrez Gene ID: (Human) 10625, (Mouse) 117198, (Rat) 289089
