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Proteintech
Iduronate 2 sulfatase Monoclonal Antibody (1A3F9)
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产品信息
66112-1-IG
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Pig,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
1A3F9
抗原
Iduronate 2 sulfatase Fusion Protein Ag19095 (1-312 aa encoded by BC006170)
偶联物
形式
Liquid
浓度
0.52 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MPPPRTGRG LLWLGLVLSS VCVALGSETQ ANSTTDALNV LLIIVDDLRP SLGCYGDKLV RSPNIDQLAS HSLLFQNAFA QQAVCAPSRV SFLTGRRPDT TRLYDFNSYW RVHAGNFSTI PQYFKENGYV TMSVGKVFHP GISSNHTDDS PYSWSFPPYH PSSEKYENTK TCRGPDGELH ANLLCPVDVL DVPEGTLPDK QSTEQAIQLL EKMKTSASPF FLAVGYHKPH IPFRYPKEFQ KLYPLENITL APDPEVPDGL PPVAYNPWMD IRQREDVQAL NISVPYGPIP VDFQEDQSST GFRLKTSSTR KYK (1-312 aa encoded by BC006170)
靶标信息
Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Alpha-L-iduronate sulfate sulfatase; Iduronate 2-sulfatase; iduronate 2-sulfatase 14 kDa chain; iduronate 2-sulfatase 42 kDa chain; iduronate sulfatase; iduronate-2-sulfatase; Idursulfase
基因别名: AW214631; IDS; MPS2; SIDS
UniProt ID: (Human) P22304, (Mouse) Q08890
Entrez Gene ID: (Pig) 100512880, (Human) 3423, (Mouse) 15931, (Rat) 363513
