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Proteintech
Inhibin beta B Polyclonal Antibody
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产品信息
17577-1-AP
应用
建议稀释比
已发表文章
产品规格
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Inhibin beta B Fusion Protein Ag10956 (51-407 aa encoded by BC030029)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.23 mg/mL
规格
34.5 µg
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: SQDTCTSCG GFRRPEELGR VDGDFLEAVK RHILSRLQMR GRPNITHAVP KAAMVTALRK LHAGKVREDG RVEIPHLDGH ASPGADGQER VSEIISFAET DGLASSRVRL YFFISNEGNQ NLFVVQASLW LYLKLLPYVL EKGSRRKVRV KVYFQEQGHG DRWNMVEKRV DLKRSGWHTF PLTEAIQALF ERGERRLNLD VQCDSCQELA VVPVFVDPGE ESHRPFVVVQ ARLGDSRHRI RKRGLECDGR TNLCCRQQFF IDFRLIGWND WIIAPTSYYG NYCEGSCPAY LAGVPGSASS FHTAVVNQYR MRGLNPGTVN SCCIPTKLST MSMLYFDDEY NIVKRDVPNM IVEECGCA (51-407 aa encoded by BC030029 )
靶标信息
The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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