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Antibodies Inc
KCC2 Monoclonal Antibody (N1/66)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
75-050
应用
建议稀释比
已发表文章
产品规格
种属反应
Chicken,
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
N1/66
抗原
Fusion protein amino acids 932-1043 (intracellular carboxyl terminus) of rat KCC2b (accession number Q63633) produced recombinantly in E. Coli.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
TBS, pH 7.4
内含物
0.065% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Dry ice (international)
产品详细信息
For maximum recovery of product, centrifuge the vial prior to removing the cap.
靶标信息
Mediates electroneutral potassium-chloride cotransport in mature neurons. Transport occurs under isotonic conditions, but is activated 20-fold by cell swelling. Important for Cl(-) homeostasis in neurons.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: electroneutral K-dependent Cl cotransporter-2; electroneutral potassium-chloride cotransporter 2; erythroid K-Cl cotransporter 2; furosemide-sensitive K-Cl cotransporter; K-Cl cotransporter 2; KCC 2; KCC2a; mKCC2; neuronal K-Cl cotransporter; neuronal-specific K-Cl cotransporter; S12A5; solute carrier family 12 (potassium-chloride transporter), member 5; solute carrier family 12 (potassium/chloride transporter), member 5; unnamed protein product
基因别名: DEE34; EIEE34; EIG14; hKCC2; KCC2; mKIAA1176
UniProt ID: (Human) Q9H2X9, (Rat) Q63633, (Mouse) Q91V14
Entrez Gene ID: (Chicken) 777252, (Human) 57468, (Rat) 171373, (Mouse) 57138
ion transport
potassium ion transport
chloride transport
hypotonic response
cellular chloride ion homeostasis
developmental process
intracellular pH reduction
transmembrane transport
dendritic spine development
potassium ion transmembrane transport
ammonium transmembrane transport
postsynaptic neurotransmitter receptor diffusion trapping
regulation of postsynapse assembly
chloride transmembrane transport
chemical synaptic transmission
learning
response to xenobiotic stimulus
multicellular organism growth
thermosensory behavior
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
