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Alomone Labs, LTD
KCNT1 (Slack) Polyclonal Antibody
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KCNT1 (Slack) Antibody (APC-124-200UL) in IHC (F)
Expression of KCNT1 (Slack) in rat cerebellum. Immunohistochemical staining of perfusion-fixed frozen rat brain sections with Anti-KCNT1 (Slack) Antibody (#APC-124), (1:300), followed by goat Anti-rabbit-AlexaFluor-488. A. KCNT1 (Slack) immunoreactivity (green) appears in the molecular layer (MOL) and Purkinje cells (arrows). B. Pre-incubation of the Antibody with KCNT1/Slack Blocking Peptide (#BLP-PC124), ... View More
产品信息
APC-124-200UL
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)KQEEKQNRRGLAG, corresponding to amino acid residues 619-631 of rat Slack, Intracellular, C-terminus
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a sodium-activated potassium channel subunit which is thought to function in ion conductance and developmental signaling pathways. Mutations in this gene cause the early-onset epileptic disorders, malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: KCa4.1KIAA1422FLJ41282; Potassium channel subfamily T member 1; potassium channel subunit (Slack); potassium channel, subfamily T, member 1; Sequence like a calcium-activated potassium channel subunit; Slo2.2
基因别名: C030030G16Rik; Kcnt1; Kiaa1422; rSlo2; Slack; slo2; Slo2.2
UniProt ID: (Mouse) Q6ZPR4, (Rat) Q9Z258
Entrez Gene ID: (Mouse) 227632, (Rat) 60444
