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Invitrogen
KDM6A Polyclonal Antibody
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产品信息
PA5-68598
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
synthetic peptide directed towards the middle region of human KDM6A (aa 245-294)
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Rabbit: 100%; Rat: 100%
This antibody is 100% homologous to isoforms 1 and 2.
靶标信息
This gene is located on the X chromosome and is the corresponding locus to a Y-linked gene which encodes a tetratricopeptide repeat (TPR) protein. The encoded protein of this gene contains a JmjC-domain and catalyzes the demethylation of tri/dimethylated histone H3.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 4lysine (K)-specific demethylase 6A; [histone H3]-trimethyl-L-lysine(27) demethylase 6A; Histone demethylase UTX; Lysine-specific demethylase 6A; ubiquitously transcribed tetratricopeptide repeat gene, X chromosome; Ubiquitously transcribed TPR protein on the X chromosome; Ubiquitously transcribed X chromosome tetratricopeptide repeat protein
基因别名: Kdm6a; Utx
UniProt ID: (Mouse) O70546
Entrez Gene ID: (Mouse) 22289
sulfonate dioxygenase activity
RNA polymerase II core promoter proximal region sequence-specific DNA binding
chromatin binding
protein binding
oxidoreductase activity
2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity
procollagen-proline dioxygenase activity
hypophosphite dioxygenase activity
identical protein binding
DNA-N1-methyladenine dioxygenase activity
metal ion binding
dioxygenase activity
C-19 gibberellin 2-beta-dioxygenase activity
C-20 gibberellin 2-beta-dioxygenase activity
histone demethylase activity (H3-K27 specific)
chromatin/chromatin-binding, or -regulatory protein
in utero embryonic development
neural tube closure
heart morphogenesis
respiratory system process
heart development
regulation of gene expression
chromatin modification
neural tube development
somite rostral/caudal axis specification
multicellular organism growth
mesodermal cell differentiation
embryonic organ development
notochord morphogenesis
oxidation-reduction process
canonical Wnt signaling pathway
histone H3-K27 demethylation
cardiovascular system development
