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Proteintech
KHDRBS3 Polyclonal Antibody
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产品信息
13563-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KHDRBS3 Fusion Protein Ag4438 (1-346 aa encoded by BC032606)
偶联物
形式
Liquid
浓度
0.22 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
This antibody is a rabbit polyclonal antibody raised against a full-length human KHDRBS3 protein. The observed molecular weight of KHDRBS is about 55 kDa.
Immunogen sequence: MEEKYLPEL MAEKDSLDPS FTHALRLVNQ EIEKFQKGEG KDEEKYIDVV INKNMKLGQK VLIPVKQFPK FNFVGKLLGP RGNSLKRLQE ETLTKMSILG KGSMRDKAKE EELRKSGEAK YFHLNDDLHV LIEVFAPPAE AYARMGHALE EIKKFLIPDY NDEIRQAQLQ ELTYLNGGSE NADVPVVRGK PTLRTRGVPA PAITRGRGGV TARPVGVVVP RGTPTPRGVL STRGPVSRGR GLLTPRARGV PPTGYRPPPP PPTQETYGEY DYDDGYGTAY DEQSYDSYDN SYSTPAQSGA DYYDYGHGLS EETYDSYGQE EWTNSRHKAP SARTAKGVYR DQPYGRY (1-346 aa encoded by BC032606)
靶标信息
As a RNA-binding protein, KHDRBS3 plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. KHDRBS3 may play a role as a negative regulator of cell growth. It inhibits cell proliferation and involved in splice site selection of vascular endothelial growth factor. It induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. It also involved in post-transcriptional regulation of HIV-1 gene expression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: etoile; etoile, Sam68-like protein SLM-2; KH domain containing, RNA binding, signal transduction associated 3; KH domain-containing, RNA-binding, signal transduction-associated protein 3; RNA-binding protein Etoile; RNA-binding protein T-Star; rSLM-2; Sam68-like mammalian protein 2; Sam68-like phosphotyrosine protein; Sam68-like phosphotyrosine protein, T-STAR; SLM-2
基因别名: Etle; etoile; KHDRBS3; SALP; SLM-2; SLM2; T-STAR; TSTAR
UniProt ID: (Human) O75525, (Rat) Q9JLP1, (Mouse) Q9R226
Entrez Gene ID: (Human) 10656, (Rat) 64015, (Mouse) 13992
