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Abnova
KHDRBS3 Polyclonal Antibody, MaxPab™
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产品信息
H00010656-B01P
产品规格
种属反应
Human,
Rat
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KHDRBS3 (NP_006549, 1 a.a. approximately 346 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MEEKYLPELM AEKDSLDPSF THALRLVNQE IEKFQKGEGK DEEKYIDVVI NKNMKLGQKV LIPVKQFPKF NFVGKLLGPR GNSLKRLQEE TLTKMSILGK GSMRDKAKEE ELRKSGEAKY FHLNDDLHVL IEVFAPPAEA YARMGHALEE IKKFLIPDYN DEIRQAQLQE LTYLNGGSEN ADVPVVRGKP TLRTRGVPAP AITRGRGGVT ARPVGVVVPR GTPTPRGVLS TRGPVSRGRG LLTPRARGVP PTGYRPPPPP PTQETYGEYD YDDGYGTAYD EQSYDSYDNS YSTPAQSGAD YYDYGHGLSE ETYDSYGQEE WTNSRHKAPS ARTAKGVYRD QPYGRY
靶标信息
As a RNA-binding protein, KHDRBS3 plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. KHDRBS3 may play a role as a negative regulator of cell growth. It inhibits cell proliferation and involved in splice site selection of vascular endothelial growth factor. It induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. It also involved in post-transcriptional regulation of HIV-1 gene expression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: etoile, Sam68-like protein SLM-2; KH domain containing, RNA binding, signal transduction associated 3; KH domain-containing, RNA-binding, signal transduction-associated protein 3; RNA-binding protein T-Star; rSLM-2; Sam68-like mammalian protein 2; Sam68-like phosphotyrosine protein; Sam68-like phosphotyrosine protein, T-STAR; SLM-2
基因别名: Etle; etoile; KHDRBS3; SALP; SLM-2; SLM2; T-STAR; TSTAR
UniProt ID: (Human) O75525, (Rat) Q9JLP1
Entrez Gene ID: (Human) 10656, (Rat) 64015
