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Invitrogen
KIR2DL3 Monoclonal Antibody (190IIC311)
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产品信息
MA5-28120
产品规格
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
190IIC311
抗原
Recombinant human KIR2DL3
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Clone 190IIC311 reacts with an extracellular domain of KIR2DL3 but does not recognize related KIR2DL family members KIR2DL1 and KIR2DS4.
Mouse anti Human CD158b antibody, clone 190IIC311 recognizes human KIR2DL3, also known as KIR-K7.
靶标信息
NKAT (NK-associated transcripts) gene products, known as killer immuno-globulin-like receptors or KIRs, downregulate the cytotoxicity of NK cells upon recognition of specific class I major histocompatibility complex (MHC) molecules on target cells. This family of receptors is characterized by an extracellular region with two to three immunoglobulin-superfamily domains and a cytoplasmic domain with an antigen receptor activation motif (ARAM). KIRs and other inhibitory receptors also possess a common cytoplasmic sequence (I/VxYxxL/V) known as an ITIM (immunoreceptor tyrosine-based inhibitory motif). The human inhibitory human killer cell immunoglobulin-like receptor 2DL3 (KIR2DL3), also referred to as CD158b, is an inhibitory receptor that is specific for the human MHC class I molecule HLA-Cw3 and related alleles.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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