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Invitrogen
KIR2DL4 Polyclonal Antibody
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图: 1 / 3
KIR2DL4 Antibody (PA5-28190) in ICC/IF
KIR2DL4 Polyclonal Antibody detects KIR2DL4 protein at cytoplasm by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: KIR2DL4 protein stained by KIR2DL4 Polyclonal Antibody (Product # PA5-28190) diluted at 1:500. Blue: Hoechst 33342 staining.
产品信息
PA5-28190
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the Extracellular domain of human KIR2DL4. The exact sequence is proprietary.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.9 mg/mL
规格
90 µg
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: THP-1.
Predicted reactivity: Rhesus Monkey (89%), Chimpanzee (96%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
CD158d / KIR2DL4 is a KIR family member that shares structural features with both activating and inhibitory receptors and may mediate different functions under different circumstances. It contains cytoplasmic ITIM, suggesting inhibitory function, but also transmembrane domain similar to those of activating KIRs. It has been reported that CD158d serves as an inhibitory receptor for peripheral and uterine NK cells, but its ligation with soluble mAbs (unlike immobilized mAbs) results in activation of IFN-gamma secretion. CD158d also binds both membrane form and soluble form of its ligand HLA-G.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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