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Invitrogen
KLF11 Polyclonal Antibody
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产品信息
PA5-101058
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human KLF11(Accession O14901), corresponding to amino acid residues M1-T36.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total KLF11.
靶标信息
The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: klf11; Krueppel-like factor 11; Kruppel-like factor 11; TGFB inducible early growth response 2; TGFB inducible early growth response 3; TGFB-inducible early growth response protein 2; TGFB-inducible early growth response protein 2b; TGFB-inducible early growth response protein 3; TIEG-2; TIEG-3; Transforming growth factor-beta-inducible early growth response protein 2; Transforming growth factor-beta-inducible early growth response protein 3
基因别名: 9830142A17; D12Ertd427e; FKLF; FKLF1; KLF11; MODY7; TIEG2; Tieg2b; Tieg3
UniProt ID: (Human) O14901, (Mouse) Q8K1S5
Entrez Gene ID: (Human) 8462, (Mouse) 194655
regulation of transcription involved in G1/S transition of mitotic cell cycle
negative regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
apoptotic process
negative regulation of cell proliferation
positive regulation of apoptotic process
transcription, DNA-templated
regulation of transcription, DNA-templated
hemopoiesis
negative regulation of transcription, DNA-templated
