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Invitrogen
KLF3 Recombinant Rabbit Monoclonal Antibody (4U8A10)
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KLF3 Antibody (MA575785) in WB
Western blot analysis of KLF3 in Mouse colon (25 μg per lane). Samples were blocked with 3% nonfat dry milk in TBST, incubated with monoclonal KLF3 (Product # MA575785) antibody at a dilution of 1:13,000 (overnight at 4°C), followed by HRP-conjugated Goat anti-Rabbit IgG (H+L) (1:10,000) and ECL. Exposure time: 45s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA575785
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
4U8A10
抗原
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.35 mg/mL
规格
135 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 0.05% BSA, 50% glycerol
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Krueppel-like factors (KLFs) comprise a family of evolutionarily conserved zinc finger-containing transcription factors with diverse regulatory functions in cell growth, proliferation, differentiation and embryogenesis. Individual members of the Sp1-like/KLF family can function either as activators or repressors, depending on which promoter they bind and the coregulators with which they interact. KLF6, also designated Zf9 or CPBP (core promoter-binding protein), and KLF3 are Kruppel-like zinc finger containing transcription factors. KLF6 is rapidly induced during hepatic stellate cell activation and transactivates a reporter gene driven by the collagen I promoter, suggesting KLF6 plays a role in the response to tissue injury. KLF3 may play a role in hematopoiesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: basic krueppel-like factor; Basic Kruppel- like factor; CACCC-box-binding protein BKLF; Kruppel like factor 3; Kruppel-like factor 3 (basic); MGC48279; unnamed protein product
基因别名: 9930027G08Rik; Bklf; Tef-2
UniProt ID: (Mouse) Q60980
Entrez Gene ID: (Mouse) 16599, (Rat) 114845
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
sequence-specific double-stranded DNA binding
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