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This gene encodes a kelch domain-containing protein which is upregulated in cancer. Upregulated expression of the encoded protein may provide an alternative pathway for tumors to maintain aggressiveness in the absence of epidermal growth factor receptor dependence. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Kelch domain-containing protein 8A; S-delta-E1; Substitute for delta-EGFR expression 1
基因别名: A630065K24Rik; KLHDC8A; RGD1305132
UniProt ID: (Human) Q8IYD2, (Mouse) Q91XA8
Entrez Gene ID: (Human) 55220, (Rat) 305096, (Mouse) 213417