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Proteintech
KLHL12 Polyclonal Antibody
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产品信息
14883-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLHL12 Fusion Protein Ag6658 (217-568 aa encoded by BC004175)
偶联物
形式
Liquid
浓度
0.36 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: NLLQYVRMP LLTPRYITDV IDAEPFIRCS LQCRDLVDEA KKFHLRPELR SQMQGPRTRA RLGANEVLLV VGGFGSQQSP IDVVEKYDPK TQEWSFLPSI TRKRRYVASV SLHDRIYVIG GYDGRSRLSS VECLDYTADE DGVWYSVAPM NVRRGLAGAT TLGDMIYVSG GFDGSRRHTS MERYDPNIDQ WSMLGDMQTA REGAGLVVAS GVIYCLGGYD GLNILNSVEK YDPHTGHWTN VTPMATKRSG AGVALLNDHI YVVGGFDGTA HLSSVEAYNI RTDSWTTVTS MTTPRCYVGA TVLRGRLYAI AGYDGNSLLS SIECYDPIID SWEVVTSMGT QRCDAGVCVL REK (217-568 aa encoded by BC004175)
靶标信息
Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.Tissue specificity: Highly expressed in testis and at lower levels in the submandibular salivary gland.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: CUL3-interacting protein 1; DKIR homolog; FLJ27152; hDKIR; kelch-like 12; kelch-like family member 12; Kelch-like protein 12; kelch-like protein C3IP1
基因别名: C3IP1; DKIR; KLHL12
UniProt ID: (Human) Q53G59, (Mouse) Q8BZM0, (Rat) Q8R2H4
Entrez Gene ID: (Human) 59349, (Mouse) 240756, (Rat) 266772
