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Invitrogen
KLHL12 Polyclonal Antibody
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产品信息
PA5-67166
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: FAETHNCVDLM QAAEVFSQKH FPEVVQHEEF ILLSQGEVEK LIKCDEIQVD SEEPV
Highest antigen sequence identity to the following orthologs - mouse 100%, rat 100%.
靶标信息
Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.Tissue specificity: Highly expressed in testis and at lower levels in the submandibular salivary gland.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CUL3-interacting protein 1; DKIR homolog; FLJ27152; hDKIR; kelch-like family member 12; Kelch-like protein 12; kelch-like protein C3IP1
基因别名: C3IP1; DKIR; KLHL12
UniProt ID: (Human) Q53G59
Entrez Gene ID: (Human) 59349
