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Proteintech
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Immunogen sequence: GGVMYISGG ITHDTFQKEL MCFDPDTDKW IQKAPMTTVR GLHCMCTVGE RLYVIGGNHF RGTSDYDDVL SCEYYSPILD QWTPIAAMLR GQSDVGVAVF ENKIYVVGGY SWNNRCMVEI VQKYDPDKDE WHKVFDLPES LGGIRACTLT VFPPEETTPS PSRESPLSAP (487-655 aa encoded by BC008729)
This gene encodes a BTB and kelch domain containing protein and belongs to the kelch repeat domain containing superfamily of proteins. The encoded protein functions as an adaptor protein that complexes with Cullin 3 and other proteins to form the Cullin 3-based E3 ubiquitin-protein ligase complex. This complex is necessary for proper chromosome segregation and completion of cytokinesis. Alternate splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: BTB and kelch domain containing 2; BTB and kelch domain-containing protein 2; FLJ10262; kelch-like 13; kelch-like family member 13; Kelch-like protein 13; MGC74791
基因别名: 1200009K10Rik; AI451128; BKLHD2; D130072F20Rik; KIAA1309; KLHL13; mKIAA1309
UniProt ID: (Human) Q9P2N7, (Mouse) Q80TF4
Entrez Gene ID: (Human) 90293, (Rat) 313445, (Mouse) 67455