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Invitrogen
KLHL22 Monoclonal Antibody (7B10)
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产品信息
MA5-15699
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
7B10
抗原
Purified recombinant fragment of human KLHL22 expressed in E. Coli.
偶联物
形式
Liquid
浓度
Conc. Not Determined
保存液
ascites
内含物
0.03% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
MA5-15699 targets KLHL22 in indirect ELISA, IF and WB applications and shows reactivity with Human samples.
The MA5-15699 immunogen is purified recombinant fragment of human KLHL22 expressed in E. Coli.
MA5-15699 detects KLHL22 which has a predicted molecular weight of approximately 72kDa.
靶标信息
KLHL22 (kelch-like protein 22) is a 634 amino acid protein that is related to the Drosophila kelch protein, which is required to maintain Actin organization in ovarian ring canals. Mutations affecting Kelch function result in the failure of Kelch to associate with the ring canals and subsequent female sterility. Human KLHL22 protein contains six kelch repeats and one BTB (POZ) domain. The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. There are two isoforms of KLHL22 that are produced as a result of alternative splicing events.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: kelch-like 22; kelch-like family member 22; Kelch-like protein 22
基因别名: 2610318I18Rik; KELCHL; KLHL22
UniProt ID: (Human) Q53GT1, (Mouse) Q99JN2
Entrez Gene ID: (Human) 84861, (Mouse) 224023
