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Immunogen sequence: VAQSEQQGEA ALSDARCKLA ELEGALQKAK QDMACLIREY QEVMNSKLGL DIEIATYRRL LEGEEQRLCE GIGAVNVCVS SSRGGVVCGD LCVSGSRPVT G
Positive Samples: Raji, A-549
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ghHb1; ghHKb1; Hair keratin K2.9; hard keratin, type II, 1; K81; keratin 81, type II; keratin complex 2, basic, gene 19; Keratin, hair, basic, 1; Keratin, type II cuticular Hb1; Keratin-81; krt81; Metastatic lymph node 137 gene protein; MLN 137; Type II hair keratin Hb1; Type-II keratin Kb21
基因别名: AA589625; ghHkb1; Hb-1; HB1; hHAKB2-1; Krt2-19; KRT81; KRTHB1; MLN137
UniProt ID: (Human) Q14533, (Mouse) Q9ERE2
Entrez Gene ID: (Human) 3887, (Mouse) 64818