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Progen
KRT9 Antibody Cocktail
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产品信息
651104
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ Ig Mix
分类
Cocktail
类型
Antibody
克隆号
Ks9.70+Ks9.216
抗原
Synthetic Peptides [(1) Amino Acids Pos. 450-477 And (2) N-Terminal Amino Acids Nos. 4-28] Of Human Keratin K9 (Mw 62,129; Formerly Also Designated Cytokeratin 9)
偶联物
形式
Liquid
浓度
Conc. Not Determined
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
651104 is a mixture of monoclonal antibodies that target KRT9.
Specificity: palmoplantar epidermal distribution and differentiation. Specifically reactive in the middle/upper suprabasal layers (stratum spinosum/granulosum) of the epidermis of palm and sole. K9 can be detected in primary cultures of palmoplantar keratinocytes when they shift to differentiation-promoting conditions and grow stratified (upper cells). K9 has not been found in normal, i.e. non-pathogenic, non-ridged epidermis, beside some minor cells surrounding the acrosyringeal ducts. No labelling has been found in epithelial cells of other stratified epithelia such as oesophagus or complex epithelia (e.g. urothelium) or in ductal or simple epithelia. Negative tissues include: muscle, liver and duodenum.The antibody cocktail is an excellent new tool to characterize primary cultures of keratinocytes/skin transplants for application in burn treatment.
靶标信息
Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CK-9; cytokeratin 9; Cytokeratin-9; K9; keratin 9, type I; Keratin, type I cytoskeletal 9; Keratin-9; type I cytoskeletal 9
基因别名: CK-9; EPPK; K9; KRT9
UniProt ID: (Human) P35527
Entrez Gene ID: (Human) 3857
