Hybridoma produced by the fusion of splenocytes from mice immunized with cytokeratin enriched extract of feline tongue epithelium and mouse myeloma cells.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5-2 mg/mL

纯化类型

Protein A/G

保存液

PBS

内含物

0.08% sodium azide

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

This antibody detects Keratin 5 and 14 by Western blot at 58 kDa, corresponding to Keratin 5, and 50 kDa, corresponding to Keratin 14. Does not work on paraffin embedded tissue sections.

靶标信息

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: 58 kDa cytokeratin; CK-14; CK-5; cytokeratin 14; cytokeratin 5; Cytokeratin-14; Cytokeratin-5; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; epidermolysis bullosa simplex, Dowling-Meara, Koebner; K14; K5; keratin 14, type I; keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5, type II; keratin complex 1, acidic, gene 14; keratin complex 2, basic, gene 5; Keratin, type I cytoskeletal 14; Keratin, type II cytoskeletal 5; Keratin-14; Keratin-5; krt5; tuftelin interacting protein 8; Type-II keratin Kb5

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基因别名: 3300001P10Rik; AI626930; AW146334; CK14; CK5; DDD; DDD1; EBS2; EBS3; EBS4; K14; K5; Krt-1.14; Krt1-14; KRT14; Krt2-5; KRT5; KRT5A; NFJ; Tfip8