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Invitrogen
Ku80 Polyclonal Antibody
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Ku80 Antibody (PA5-35087) in ICC/IF
Immunofluorescent analysis of XRCC5 in Hela cells using a XRCC5 polyclonal antibody (Product # PA5-35087) followed by detection using a fluorescent conjugated secondary antibody (green). Nuclei were stained with Dapi (blue) and cytoplasmic actin was stained with a fluorescent phalloidin (red).
产品信息
PA5-35087
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 424-450 amino acids from the central region of human XRCC5
偶联物
形式
Liquid
浓度
Lot-specific
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
靶标信息
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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