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Antibodies Inc
Kv3.4 K+ Channel Monoclonal Antibody (N72/16)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
75-112
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
N72/16
抗原
Synthetic peptide amino acids 175-192 of rat Kv3.4 (accession number Q63734).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
TBS, pH 7.4
内含物
0.065% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Dry ice (international)
产品详细信息
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Sequence of this protein is as follows: GDEAGDDERE LALQRLGP
靶标信息
The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Several transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: K+ channel subunit; MGC126818; potassium channel, voltage gated Shaw related subfamily C, member 4; potassium channel, voltage gated Shaw-related subfamily C, member 4; potassium voltage gated channel, Shaw-related subfamily, member 4; potassium voltage-gated channel subfamily C member 4; potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (Raw3); potassium voltage-gated channel, Shaw-related subfamily, member 4; raw3; unnamed protein product; voltage-gated potassium channel subunit KV3.4
基因别名: C1orf30; HKSHIIIC; Kcr2-4; KSHIIIC; KV3.4
UniProt ID: (Human) Q03721, (Rat) Q63734, (Mouse) Q8R1C0
Entrez Gene ID: (Human) 3749, (Rat) 684516, (Mouse) 99738
ion channel activity
voltage-gated potassium channel activity
delayed rectifier potassium channel activity
potassium channel activity
protein binding
gated channel activity
voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
action potential
ion transport
potassium ion transport
optic nerve development
cerebral cortex development
corpus callosum development
forebrain development
regulation of neurotransmitter secretion
protein homooligomerization
transmembrane transport
regulation of postsynaptic membrane potential
axon development
potassium ion transmembrane transport
regulation of presynaptic membrane potential
negative regulation of neuronal action potential
chemical synaptic transmission
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