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Proteintech
LARG Polyclonal Antibody
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产品信息
22441-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
LARG Fusion Protein Ag18211 (214-563 aa encoded by BC063117)
偶联物
形式
Liquid
浓度
0.49 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: QRLLKEIQE AKKHIPQLQE QLSKATGSAQ DGAVVTPSRP LGDTLTVSEA ETDPGDVLGR TDCSSGDASR PSSDNADSPK SGPKERIYLE ENPEKSETIQ DTDTQSLVGS PSTRIAPHII GAEDDDFGTE HEQINGQCSC FQSIELLKSR PAHLAVFLHH VVSQFDPATL LCYLYSDLYK HTNSKETRRI FLEFHQFFLD RSAHLKVSVP DEMSADLEKR RPELIPEDLH RHYIQTMQER VHPEVQRHLE DFRQKRSMGL TLAESELTKL DAERDKDRLT LEKERTCAEQ IVAKIEEVLM TAQAVEEDKS STMQYVILMY MKHLGVKVKE PRNLEHKRGR IGFLPKIKQS M (214-563 aa encoded by BC063117)
靶标信息
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: leukemia-associated rho guanine nucleotide exchange factor; Leukemia-associated RhoGEF; Rho guanine nucleotide exchange factor (GEF) 12; Rho guanine nucleotide exchange factor 12
基因别名: ARHGEF12; KIAA0382; LARG; PRO2792
UniProt ID: (Human) Q9NZN5
Entrez Gene ID: (Human) 23365
