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Proteintech
LCAT Polyclonal Antibody
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产品信息
12243-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
LCAT Fusion Protein Ag2887 (94-440 aa encoded by BC014781)
偶联物
形式
Liquid
浓度
0.13 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: LGVDCWIDN TRVVYNRSSG LVSNAPGVQI RVPGFGKTYS VEYLDSSKLA GYLHTLVQNL VNNGYVRDET VRAAPYDWRL EPGQQEEYYR KLAGLVEEMH AAYGKPVFLI GHSLGCLHLL YFLLRQPQAW KDRFIDGFIS LGAPWGGSIK PMLVLASGDN QGIPIMSSIK LKEEQRITTT SPWMFPSRMA WPEDHVFIST PSFNYTGRDF QRFFADLHFE EGWYMWLQSR DLLAGLPAPG VEVYCLYGVG LPTPRTYIYD HGFPYTDPVG VLYEDGDDTV ATRSTELCGL WQGRQPQPVH LLPLHGIQHL NMVFSNLTLE HINAILLGAY RQGPPASPTA SPEPPPPE (94-440 aa encoded by BC014781 )
靶标信息
Lecithin: cholesterol acyltransferase (LCAT) is the plasma enzyme responsible for most HDL cholesteryl esters in human plasma. In species with cholesteryl ester transfer protein (CETP) it is also responsible for a significant proportion of VLDL and LDL cholesteryl esters. LCAT, through the esterification of cholesterol, plays a role in the reverse cholesterol transport pathway by facilitating the net movement of cholesterol from peripheral tissues back to the liver for excretion. LCAT deficiency results in low levels of plasma HDL, whereas a transgenic overexpression of LCAT results in increased plasma HDL concentrations.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 1-alkyl-2-acetylglycerophosphocholine esterase; Lecithin-cholesterol acyltransferase; lecithin-cholesterol acyltransferase Lcat; PAF acetylhydrolase; phosphatidylcholine--sterol O-acyltransferase; Phosphatidylcholine-sterol acyltransferase; Phospholipid-cholesterol acyltransferase; Platelet-activating factor acetylhydrolase; testicular secretory protein Li 24
基因别名: AI046659; D8Wsu61e; LCAT
UniProt ID: (Human) P04180, (Rat) P18424, (Mouse) P16301
Entrez Gene ID: (Human) 3931, (Rat) 24530, (Mouse) 16816
phospholipid metabolic process
phosphatidylcholine biosynthetic process
cholesterol metabolic process
cholesterol transport
very-low-density lipoprotein particle remodeling
high-density lipoprotein particle remodeling
cholesterol esterification
lipoprotein metabolic process
lipoprotein biosynthetic process
cholesterol homeostasis
reverse cholesterol transport
phosphatidylcholine metabolic process
response to copper ion
response to glucocorticoid
regulation of high-density lipoprotein particle assembly
lipid metabolic process
steroid metabolic process
