Immunogen sequence: NSQLMEQLRL LVCERASLLR QVRPPSCPVP FPETFNGESS RLPEFIV

Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 74%.

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LDOC1 contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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LDOC1 Polyclonal Antibody

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PA5-62475

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