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Proteintech
LGR4 Polyclonal Antibody
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产品信息
20150-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
LGR4 Fusion Protein Ag13695 (27-376 aa encoded by BC033039)
偶联物
形式
Liquid
浓度
0.23 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: PLCAAPCSC DGDRRVDCSG KGLTAVPEGL SAFTQALQLA GNDLSFIHPK ALSGLKELKV LTLQNNQLKT VPSEAIRGLS ALQSLRLDAN HITSVPEDSF EGLVQLRHLW LDDNSLTEVP VHHLSNLPTL QALTLALNKI SSIPDFAFTN LSSLVVLHLH NNKIRSLSQH CFDGLDNLET LDLNYNNLGE FPQAIKALPS LKELGFHSNS ISVIPDGAFD GNPLLRTIHL YDNPLSFVGN SAFHNLSDLH SLVIRGASMV QQFPNLTGTV HLESLTLTGT KISSIPNNLC QEQKMLRTLD LSYNNIRDLP SFNGCHALEE ISLQRNQIYQ IKEGTFQGLI SLRILDLSRN L (27-376 aa encoded by BC033039)
靶标信息
G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. GPCR LGR4 is a member of this family (subfamily Orphan-A). Its expression has been documented in human brain, adrenal, heart, kidney, liver, skeletal muscle, ovary, pancreas, placenta, prostate, spleen, stomach, testis, thyroid, and spinal cord.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: G protein-coupled receptor 48; G protein-coupled receptor GPR48; G-protein coupled receptor 48; leucine-rich repeat containing G protein-coupled receptor 4; Leucine-rich repeat-containing G-protein coupled receptor 4
基因别名: 9130225G07; A330106J01Rik; A930009A08Rik; BNMD17; GPR48; LGR4
UniProt ID: (Human) Q9BXB1, (Mouse) A2ARI4, (Rat) Q9Z2H4
Entrez Gene ID: (Human) 55366, (Mouse) 107515, (Rat) 286994
osteoblast differentiation
hair follicle development
G-protein coupled receptor signaling pathway
spermatogenesis
bone mineralization
male genitalia development
circadian regulation of gene expression
negative regulation of toll-like receptor signaling pathway
intestinal stem cell homeostasis
innate immune response
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
bone remodeling
digestive tract development
negative regulation of cytokine secretion
canonical Wnt signaling pathway involved in metanephric kidney development
cell differentiation involved in metanephros development
metanephric glomerulus development
metanephric nephron tubule morphogenesis
positive regulation of branching involved in ureteric bud morphogenesis
positive regulation of canonical Wnt signaling pathway
epithelial cell proliferation involved in renal tubule morphogenesis
immune system process
signal transduction
multicellular organism development
Wnt signaling pathway
cell differentiation
tube morphogenesis
rhythmic process
epithelial cell proliferation
biological_process
