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Invitrogen
LHR Polyclonal Antibody
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产品信息
PA5-79598
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence at the N-terminus of human hCG receptor (127-143aa YLSICNTGIRKFPDVTK).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide, 0.05mg thimerosal
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: MCF-7 whole cell. IHC: Rat Ovary Tissue.
靶标信息
LHCGR encodes the receptor for both luteinizing hormone and choriogonadotropin. It is family 1 of G-protein coupled receptors, FSH/LSH/TSH superfamily, and its basic function is acting as luteinizing hormone/choriogonadotropin receptor (gonadotropin receptor). Regulating the development and function of Leyding cells in males. It also plays a role in male secondary sexual characterdevelopment. Mutations in this gonadotropinreceptor results in disorders of male secondary sexual characteristic development, such as familial male precocious puperty and male pseudohermaphtoditism.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HCG receptor; hypergonadotropic hypogonadism; LH receptor; LH/CG-R; LHR; LSH-R; Luteinizing hormone receptor; Lutropin receptor; Lutropin-choriogonadotropic hormone receptor; lutropin/choriogonadotropin receptor
基因别名: HHG; LCGR; LGR2; LH/CG-R; LH/CGR; LHCGR; LHR; LHRHR; LSH-R; LSHR; ULG5
UniProt ID: (Human) P22888, (Rat) P16235
Entrez Gene ID: (Human) 3973, (Rat) 25477
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-activating G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
phospholipase C-activating G-protein coupled receptor signaling pathway
male gonad development
hormone-mediated signaling pathway
ovulation cycle process
male genitalia development
positive regulation of inositol trisphosphate biosynthetic process
luteinizing hormone signaling pathway
positive regulation of cAMP-mediated signaling
cognition
cellular response to gonadotropin stimulus
ovarian follicle development
protein targeting to lysosome
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
spermatogenesis
central nervous system development
female gonad development
positive regulation of calcium ion transport into cytosol
response to drug
development of secondary male sexual characteristics
positive regulation of hormone biosynthetic process
arachidonic acid secretion
regulation of steroid biosynthetic process
positive regulation of calcium-mediated signaling
positive regulation of release of sequestered calcium ion into cytosol
uterus development
seminiferous tubule development
regulation of steroid hormone biosynthetic process
