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Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7.
Predicted reactivity: Mouse (99%), Rat (99%), Xenopus laevis (94%), Pig (100%), Chicken (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Members of the LIM homeobox gene family, such as LHX8, encode transcription regulators that share common structural features. They all contain 2 tandemly repeated cysteine-rich double-zinc finger motifs, called LIM domains, in addition to a homeodomain. The homeodomain is a DNA-binding domain, and the LIM domains are essential for regulating the activity of these molecules by interacting with other proteins. Members of the LIM homeobox gene family are required for the patterning or the specification and differentiation of different cell types during embryonic development (Zhao et al., 1999 [PubMed 10611327]).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: LIM homeobox protein 8; LIM Homeodomain 8; LIM-homeodomain protein Lhx8; LIM/homeobox protein Lhx8
基因别名: LHX7; LHX8
UniProt ID: (Human) Q68G74
Entrez Gene ID: (Human) 431707