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Invitrogen
LINGO1 Monoclonal Antibody (332233)
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产品信息
MA5-61257
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
332233
抗原
Mouse myeloma cell line NS0-derived recombinant human LINGO-1, Thr40-Thr556
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Protein A/G
保存液
PBS with trehalose
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute at 0.5 mg/mL in sterile PBS.
靶标信息
Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed:14966521, PubMed:15694321). Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed:15895088). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: LERN1; leucine rich repeat neuronal 6A; leucine-rich repeat; leucine-rich repeat and immunoglobulin domain-containing protein 1; leucine-rich repeat neuronal protein 1; unnamed protein product
基因别名: LERN1; LRRN6A; MRT64; UNQ201
UniProt ID: (Human) Q96FE5
Entrez Gene ID: (Human) 84894
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