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Invitrogen
LINGO1 (extracellular) Polyclonal Antibody
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LINGO1 (extracellular) Antibody (PA5-77544) in IHC (F)
Immunohistochemistry analysis of LINGO1 (extracellular) in perfusion-fixed, frozen rat brain. Samples were probed with LINGO1 (extracellular) polyclonal antibody (Product # PA5-77544) using a dilution of 1:400, and incubated with DAPI. A) Stained substantia nigra (red). B) Stained spinal cord (arrows). Images also show stained nuclei.
产品信息
PA5-77544
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide (C)HVRSYSPDWPHQPNK, corresponding to amino acid residues 507- 521 of mouse LINGO-1
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
产品详细信息
Product is shipped at room temperature as a lyophilized powder and should be stored at -20C upon receipt.
Reconstitute using 50 uL deionized water.
靶标信息
Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed:14966521, PubMed:15694321). Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed:15895088). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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