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Invitrogen
LMTK3 Polyclonal Antibody
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产品信息
PA5-114265
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the middle region of Mouse Lmtk3
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: RGLLKSPRAA DEPEDSELER KRKMVSFHGD VTVYLFDQET PTNELSVQGT
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted homology: Cow: 100%; Guinea Pig: 93%; Human: 100%; Mouse: 93%; Pig: 100%
靶标信息
Protein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation. May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription (PubMed:21602804). Involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Apoptosis-associated tyrosine kinase 3; KIAA1883; Lemur tyrosine kinase 3; Serine/threonine-protein kinase LMTK3
基因别名: Aatyk3; BC059845; Lmtk3
UniProt ID: (Mouse) Q5XJV6
Entrez Gene ID: (Mouse) 381983
