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Invitrogen
LNPEP Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-149195
产品规格
种属反应
Human
宿主/亚型
Sheep
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Chinese hamster ovary cell line CHO-derived recombinant human Leucyl-cystinyl Aminopeptidase/LNPEP, Arg133-Gly552
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
0.2 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS with trehalose
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: angiotensin IV receptor; AT (4) receptor; cystinyl aminopeptidase; insulin-regulated aminopeptidase; insulin-regulated membrane aminopeptidase; insulin-responsive aminopeptidase; otase; oxytocinase; placental leucine aminopeptidase; unnamed protein product; vasopressinase; vp160
基因别名: CAP; IRAP; P-LAP; PLAP
UniProt ID: (Human) Q9UIQ6
Entrez Gene ID: (Human) 4012
protein polyubiquitination
antigen processing and presentation of peptide antigen via MHC class I
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
proteolysis
cell-cell signaling
female pregnancy
regulation of blood pressure
neuropeptide catabolic process
negative regulation of cold-induced thermogenesis
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