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Proteintech
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Immunogen sequence: TSAAAQLDE LMAHLTEMQA KVAVRADAGK KHLPDKQDHK ASLDSMLGGL EQELQDLGIA TVPKGHCASC QKPIAGKVIH ALGQSWHPEH FVCTHCKEEI GSSPFFERSG LAYCPNDYHQ LFSPRCAYCA APILDKVLTA MNQTWHPEHF FCSHCGEVFG AEGFHEKDKK PYCRKDFLAM FSPKCGGCNR PVLENYLSAM DTVWHPECFV CGDCFTSFST GSFFELDGRP FCELHYHHRR GTLCHGCGQP ITGRCISAMG YKFHPEHFVC AFCLTQLSKG IFREQNDKTY CQPCFNKLFP L (87-386 aa encoded by BC019035)
The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。