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Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human Raji whole cell, human PC-3 whole cell, human U87 whole cell, human MDA-MB-453 whole cell, mouse RAW2647 whole cell. Flow: Raji cell.
The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Leupaxin
基因别名: 4933402K05Rik; A530083L21Rik; AV278559; LDLP; LDPL; LPXN
UniProt ID: (Human) O60711, (Mouse) Q99N69
Entrez Gene ID: (Human) 9404, (Mouse) 107321