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Proteintech
LRRC1 Polyclonal Antibody
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产品信息
10128-2-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
LRRC1 Fusion Protein Ag0175 (16-266 aa encoded by BC003193)
偶联物
形式
Liquid
浓度
0.15 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: SIDKRHCSL VYVPEEIYRY ARSLEELLLD ANQLRELPEQ FFQLVKLRKL GLSDNEIQRL PPEIANFMQL VELDVSRNEI PEIPESISFC KALQVADFSG NPLTRLPESF PELQNLTCLS VNDISLQSLP ENIGNLYNLA SLELRENLLT YLPDSLTQLR RLEELDLGNN EIYNLPESIG ALLHLKDLWL DGNQLSELPQ EIGNLKNLLC LDVSENRLER LPEEISGLTS LTDLVISQNL LETIPDGIGK LK (16-266 aa encoded by BC003193)
靶标信息
Lano is a member of the LAP (leucine-rich repeats and PDZ) family of proteins that also includes Densin-180, Erbin, and hScribble. The LAP proteins generally contain multiple leucine-rich repeat (LRR) domains which serve to target them to the basolateral membrane of epithelial cells. Lano is unique in that it alone does not possess one or more PDZ (PSD95/DLG/ZO-1) domains as do the other members of the LAP family. However, it can bind to the PDZ domain of Erbin in addition to those of membrane-associated and guanylate kinase (MAGUK) proteins which regulate adhesion and plasticity at cell junctions. It has been suggested that it is through these interaction that these LAP proteins participate in the maintenance of proper embryonic development and integrity of epithelial tissues.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: LANO adapter protein; LAP (leucine-rich repeats and PDZ) and no PDZ protein; LAP and no PDZ protein; leucine-rich repeat-containing 1; Leucine-rich repeat-containing protein 1; RP3-523E19.1
基因别名: A430093J20Rik; AU016091; D030059I21; dJ523E19.1; LANO; LRRC1; mKIAA4018
UniProt ID: (Human) Q9BTT6, (Mouse) Q80VQ1
Entrez Gene ID: (Human) 55227, (Mouse) 214345, (Rat) 367113
