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Proteintech
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This LRRC8D antibody does not cross-react with LRRC8A.
Immunogen sequence: LQELHLCHC PAKVEQTAFS FLRDHLRCLH VKFTDVAEIP AWVYLLKNLR ELYLIGNLNS ENNKMIGLES LRELRHLKIL HVKSNLTKVP SNITDVAPHL TKLVIHNDGT KLLVLNSLKK MMNVAELELQ NCELERIPHA IFSLSNLQEL DLKSNNIRTI EEIISFQHLK RLTCLKLWHN KIVTIPPSIT HVKNLESLYF SNNKLESLPV AVFSLQKLRC LDVSYNNISM IPIEIGLLQN LQHLHITGNK VDILPKQLFK CIKLRTLNLG QNCITSLPEK VGQLSQLTQL ELKGNCLDRL PAQLGQCRML KKSGLVVEDH LFDTLPLEVK EALNQDINIP FANGI (515-858 aa encoded by BC024159)
Component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. It is unclear whether LRRC8D constitutes a pore-forming subunit or whether it is closely associated with the pore.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: HsLRRC8D; leucine rich repeat containing 5; leucine rich repeat containing 8 family; leucine rich repeat containing 8 family, member D; leucine rich repeat containing 8D; leucine-rich repeat containing 8 family member D; leucine-rich repeat-containing 5; Leucine-rich repeat-containing protein 5; Leucine-rich repeat-containing protein 8D; Volume-regulated anion channel subunit LRRC8D
基因别名: 2810473G09Rik; 4930525N13Rik; A930019F03; LRRC5; LRRC8D; UNQ213/PRO239
UniProt ID: (Human) Q7L1W4, (Mouse) Q8BGR2, (Rat) Q5U308
Entrez Gene ID: (Human) 55144, (Mouse) 231549, (Rat) 305131