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Recommended positive controls: A431.
Predicted reactivity: Mouse (93%), Rat (92%), Bovine (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: leucine-rich repeat kinase 1; Leucine-rich repeat serine/threonine-protein kinase 1; LRRK1
基因别名: KIAA1790; LRRK1; RIPK6; Roco1
UniProt ID: (Human) Q38SD2
Entrez Gene ID: (Human) 79705