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Abnova
LRRN1 Monoclonal Antibody (3D11)
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产品信息
H00057633-M05
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
3D11
抗原
LRRN1 (CAL37408.1, 1 a.a. approximately 716 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.27 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: MARMSFVIAA CQLVLGLLMT SLTESSIQNS ECPQLCVCEI RPWFTPQSTY REATTVDCND LRLTRIPSNL SSDTQVLLLQ SNNIAKTVDE LQQLFNLTEL DFSQNNFTNI KEVGLANLTQ LTTLHLEENQ ITEMTDYCLQ DLSNLQELYI NHNQISTISA HAFAGLKNLL RLHLNSNKLK VIDSRWFDST PNLEILMIGE NPVIGILDMN FKPLANLRSL VLAGMYLTDI PGNALVGLDS LESLSFYDNK LVKVPQLALQ KVPSLKFLDL NKNPIHKIQE GDFKNMLRLK ELGINNMGEL VSVDRYALDN LPELTKLEAT NNPKLSYIHR LAFRSVPALE SLMLNNNALN AIYQKTVESL PNLREISIHS NPLRCDCVIH WINSNKTNIR FMEPLSMFCA MPPEYKGHQV KEVLIQDSSE QCLPMISHDS FPNRLNVDIG TTVFLDCRAM AEPEPEIYWV TPIGNKITVE TLSDKYKLSS EGTLEISNIQ IEDSGRYTCV AQNVQGADTR VATIKVNGTL LDGTQVLKIY VKQTESHSIL VSWKVNSNVM TSNLKWSSAT MKIDNPHITY TARVPVDVHE YNLTHLQPST DYEVCLTVSN IHQQTQKSCV NVTTKNAAFA VDISDQETST ALAAVMGSMF AVISLASIAV YFAKRFKRKN YHHSLKKYMQ KTSSIPLNEL YPPLINLWEG DSEKDKDGSA DTKPTQVDTS RSYYMW
靶标信息
Leucine-rich repeat neuronal 1 (LRRN1) is a gene located on chromosome 3q23, which encodes a transmembrane protein belonging to the leucine-rich repeat (LRR) family. This protein plays a significant role in neural development and synaptic plasticity due to its involvement in cell-cell adhesion and signaling pathways. LRRN1 has been implicated in brain development processes, especially in synapse organization and neuronal differentiation. Its expression is primarily localized to the central nervous system, indicating its importance in neurodevelopmental functions. Research has highlighted LRRN1's potential involvement in cognitive functions, and alterations in its expression have been associated with various neurological disorders. Additionally, LRRN1 is thought to contribute to the establishment of neuronal networks by modulating interactions between neurons through extracellular matrix components. Current studies are exploring its contributions to neuropathological conditions, providing insights into its relevance in brain health and disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: fibronectin type III, immunoglobulin and leucine rich repeat domains 3; Leucine-rich repeat neuronal protein 1; LRN; Neuronal leucine-rich repeat protein 1; NLRR-1
基因别名: 2810047E21Rik; FIGLER3; KIAA1497; LRRN1; Nbla10449; NLRR-1; UNQ693/PRO1338
UniProt ID: (Human) Q6UXK5, (Mouse) Q61809, (Rat) Q32Q07
Entrez Gene ID: (Human) 57633, (Mouse) 16979, (Rat) 500280
