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Invitrogen
LRRTM1 (extracellular) Polyclonal Antibody
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LRRTM1 (extracellular) Antibody (PA5-111862) in IHC (F)
Immunohistochemistry analysis of LRRTM1 in perfusion-fixed, frozen rat cortex tissue sections using LRRTM1 (extracellular) Antibody (Product # PA5-111862) at a dilution of 1:200, followed by goat-anti-rabbit-AlexaFluor-488. LRRTM1 staining (green) in rat temporal cortex is detected in neuronal profiles (arrows). Cell nuclei are stained with DAPI (blue).
产品信息
PA5-111862
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide corresponding to amino acid residues 334-346 of mouse LRRTM1 (Extracellular, N-terminus)
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
产品详细信息
Reconstitute antibody with 50 µL of double distilled water (DDW). The reconstituted solution can be stored at 4 degrees C for up to 1 week. For longer periods, small aliquots should be stored at -20 degrees C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Peptide sequence is: (C)GRYDANL Q(S)ASPE
Homology: Mouse and rat - 12/13 amino acid residues identical; human - 11/13 amino acid residues identical.
靶标信息
The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Each LRRTM protein is a type I transmembrane containing ten extracellular leucine-rich repeats and a short intracellular tail and has a developmentally regulated pattern distinct from all others. LRRTM1 is a maternally suppressed gene that is associated paternally with handedness and schizophrenia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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