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Bethyl Laboratories
LRWD1 Polyclonal Antibody
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LRWD1 Antibody (A301-868A) in WB
Detection of human and mouse LRWD1 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, A-549, mouse TCMK-1, and mouse NIH 3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-LRWD1 antibody (Product # A301-868A) (lot A301-868A-2) used for WB at 0.1 µg/mL. Detection: Chemiluminescence with an exposure time of 3 minutes.
产品信息
A301-868A
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 432 and 482 of human leucine-rich repeats and WD repeat domain containing 1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
tris citrate/phosphate, pH 7-8
内含物
0.09% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
靶标信息
Required for G1/S transition. Recruits and stabilizes the origin recognition complex (ORC) onto chromatin during G1 to establish pre-replication complex (preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CENP-33; Centromere protein 33; Leucine-rich repeat and WD repeat-containing protein 1; leucine-rich repeats and WD repeat domain containing 1; ORC-associated protein; ORCA; Origin recognition complex-associated protein; testicular tissue protein Li 4
基因别名: 1200011O22Rik; AU042569; AW548074; CENP-33; LRWD1; ORCA
UniProt ID: (Human) Q9UFC0, (Mouse) Q8BUI3
Entrez Gene ID: (Human) 222229, (Mouse) 71735
