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Invitrogen
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PA5-21378 targets LTBP-4 in immunohistochemistry, immunocytochemistry, immunofluorescence, and Western blot applications and shows reactivity with Human and mouse samples.
The PA5-21378 immunogen is a recombinant fragment corresponding to a region within amino acids 101 and 323 of LTBP4 (Uniprot ID#Q8N2S1).
The protein encoded by this gene binds transforming growth factor beta (TGFB) as it is secreted and targeted to the extracellular matrix. TGFB is biologically latent after secretion and insertion into the extracellular matrix, and sheds TGFB and other proteins upon activation. Defects in this gene may be a cause of cutis laxa and severe pulmonary, gastrointestinal, and urinary abnormalities. Three transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。