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Invitrogen
LTBR Polyclonal Antibody
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产品信息
PA5-109926
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide
偶联物
形式
Liquid
浓度
0.73 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: GEQSQVAHGT NGIHVTGGSM TITGNIYIYN GPVLGGPPGP GDLPATPEPP YPIPEEGDPG PPGLSTPHQE DGKAWHLAET EHCGATPSNR GPRNQFITHD
靶标信息
The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein specifically binds the lymphotoxin membrane form (a complex of lymphotoxin-alpha and lymphtoxin-beta). The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and tranformed cells. Activation of the encoded protein can trigger apoptosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: LT beta-R; LT-beta receptor; lymphotoxin B receptor; lymphotoxin beta receptor (TNFR superfamily, member 3); Lymphotoxin-beta receptor; TNF receptor-related protein; TNF-RIII; TNFR-III; Tumor necrosis factor C receptor; Tumor necrosis factor receptor 2-related protein; Tumor necrosis factor receptor superfamily member 3; tumor necrosis factor receptor superfamily, member 3; Tumor necrosis factor receptor type III
基因别名: AI256028; CD18; D12S370; LT-BETA-R; Ltar; LTbetaR; LTBR; TNF-R-III; Tnfbr; TNFCR; TNFR-RP; TNFR2-RP; TNFR3; TNFRrp; TNFRSF3
UniProt ID: (Human) P36941, (Mouse) P50284
Entrez Gene ID: (Human) 4055, (Mouse) 17000, (Rat) 297604
apoptotic process
inflammatory response
immune response
signal transduction
multicellular organism development
viral process
response to lipopolysaccharide
tumor necrosis factor-mediated signaling pathway
regulation of cell proliferation
myeloid dendritic cell differentiation
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of JNK cascade
cellular response to mechanical stimulus
positive regulation of extrinsic apoptotic signaling pathway
lymph node development
