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Invitrogen
LTK Polyclonal Antibody
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FIGURE: 1 / 3
LTK Antibody (PA5-47646) in IHC (P)
Immunohistochemical analysis of LTK in immersion fixed paraffin-embedded sections of human brain (cortex). Samples were incubated in LTK polyclonal antibody (Product # PA5-47646) using a dilution of 10 µg/mL overnight at 4 °C. Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic . Tissue was stained using the Anti-Sheep HRP... View More
Product Details
PA5-47646
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Sheep
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant human LTK Ser10-Pro424
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
LTK (TYK1), ALK and Ros have been identified as receptor tyrosine kinases having sequence similarity to the Insulin receptor subfamily of kinases. LTK, leukocyte tyrosine kinase, is expressed in murine B-lymphocyte precursors and has also been found in forebrain neurons. ALK, anaplastic lymphoma kinase, is normally highly expressed specifically in the nervous system. A truncated form containing the catalytic domain of ALK is expressed as the result of a translocation occurring in many non-Hodgkin's lymphomas. The c-Ros gene was originally identified in mutant form as an oncogene. Ros is normally expressed in a small number of epithelial cell types and may play a role in epithelial development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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