Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
LZTS2 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
产品信息
15677-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
LZTS2 Fusion Protein Ag8145 (319-669 aa encoded by BC006212)
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: PSDEALLHC VLEGKLRDRE AELQQLRDSL DENEATMCQA YEERQRHWQR EREALREDCA AQAQRAQRAQ QLLQLQVFQL QQEKRQLQDD FAQLLQEREQ LERRCATLER EQRELGPRLE ETKWEVCQKS GEISLLKQQL KESQAELVQK GSELVALRVA LREARATLRV SEGRARGLQE AARARELELE ACSQELQRHR QEAEQLREKA GQLDAEAAGL REPPVPPATA DPFLLAESDE AKVQRAAAGV GGSLRAQVER LRVELQRERR RGEEQRDSFE GERLAWQAEK EQVIRYQKQL QHNYIQMYRR NRQLEQELQQ LSLELEAREL ADLGLAEQAP CICLEEITAT EI (319-669 aa encoded by BC006212)
靶标信息
LZTS2 is a negative regulator of katanin-mediated microtubule severing and release from the centrosome. LZTS2 is required for central spindle formation and the completion of cytokinesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: hLZTS2; Leucine zipper putative tumor suppressor 2; leucine zipper, putative tumor suppressor 2; Protein LAPSER1; putative tumor suppressor LAPSER1; RP11-108L7.8
基因别名: BC014695; KIAA1813; LAPSER1; LZTS2; mKIAA1813
UniProt ID: (Human) Q9BRK4, (Mouse) Q91YU6
Entrez Gene ID: (Human) 84445, (Mouse) 226154
cytokinesis
kidney development
mitotic nuclear division
negative regulation of cell proliferation
positive regulation of cell death
Wnt signaling pathway
microtubule severing
nuclear export
spindle midzone assembly
negative regulation of canonical Wnt signaling pathway
negative regulation of protein localization to nucleus
cell cycle
negative regulation of Wnt signaling pathway
cell division
renal system development
