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Invitrogen
Lamin A/C Monoclonal Antibody (Jol5)
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产品信息
MA1-5821
产品规格
宿主/亚型
Mouse
/ IgG2
分类
Monoclonal
类型
Antibody
克隆号
Jol5
抗原
Recombinant bacterially expressed full length protein
偶联物
形式
Liquid
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
产品详细信息
MA1-5821 detects an un-phosphorylated form of lamin A/C and the epitope is mapped to the N-terminal head domain of both proteins (aa 1-171). It reacts with mouse myoblasts (C2C12) in Western blot applications. Other cell/tissue types have not been tested in Western blot. Detects a band of approximately 70 kDa (Lamin A) and 60kDa (Lamin C).
靶标信息
Lamins are a class of intermediate filament proteins that form a matrix on the inner surface of the nuclear envelope. These proteins are found in many different cell types in three different forms (A, B, and C). Lamins A and C are alternatively spliced versions of the LMNA gene. The LMNA gene has been linked to many disorders of the muscular system, nervous system, and the fat distributions systems including: Emery-Dreifuss muscular dystrophy, Dunnigan-type familial partial lipodystrophy (FPLD), limb-girdle muscular dystrophy (LGMD1B), dilated cardiomyopathy (CMD1A), axonal neuropathy (Charcot-Marie-Tooth disease; CMT2B1), and mandibuloacral dysplasia (MAD).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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